Effect of donor STAT4 polymorphism rs7574865 on clinical outcomes of pediatric acute leukemia patients after hematopoietic stem cell transplant
نویسندگان
چکیده
منابع مشابه
Pediatric Hematopoietic Stem Cell Transplantation
The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
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Background: Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) is used as treatment of choice for patients with acute myeloid leukemia (AML). We aimed to evaluate the prognostic factors in 2-year overall survival of patients with non-M3 AML who underwent allogenic HSCT. Methods: This is a Cross sectional retrospective study. Demographic data and study of variables such as age...
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چکیده ندارد.
15 صفحه اولHematopoietic stem cell transplant therapy, clinical trials, complications, and quality of life for patients with Sickle cell anemia: Clinical potential and future perspectives
Background: Sickle cell anemia (SCA) is an inherited monogenic disorder. The clinical symptoms of SCA are protean, including vaso-occlusion, hemolysis, early stroke, leg ulcers, multi-organ failure, and increased risk of premature death. Hematopoietic stem cell transplantation is the only treatment identified to reduce SCA-related organ damage. Unfortunately, graft rejection is a significant im...
متن کاملSTAT4 rs7574865 polymorphism and the susceptibility of systemic sclerosis (SSc)
Previous study suggested that signal transducers and activators of transcription-4 (STAT4) rs7574865 polymorphism may play an important role in susceptibility to Systemic Sclerosis (SSc) in Chinese. However, no further study was conducted to confirm this result. Thus, we did a case-control study. 174 SSc patients and 202 controls were enrolled in this study. When the STAT4 rs7574865 polymorphis...
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ژورنال
عنوان ژورنال: International Immunopharmacology
سال: 2017
ISSN: 1567-5769
DOI: 10.1016/j.intimp.2016.12.007